Day twelve of stimulation, day seven of cetrotide and trigger shot (ovitrelle) day!
This is going to be a rather short and sweet post.
Despite it being less than month since our first consultation at The Lister we are now galloping towards the IVF finish line. It's felt intense, the jabs have hurt more this time round (yes they bruise and I normally bleed after each and every one, my belly also goes bright red and itchy immediately afterwards). Despite a lower dose I have been responding well but I am very glad to not have to jab myself for a good while after today - fingers crossed. Today is the first working day since last week that I haven't be required at hospital, it feels strange. I had roughly 14 follicles that looked ripe for harvesting at my scan yesterday, my hormone levels have been balancing out, I'm learning to relax and I'm trying not to fret about not being at work.
I'm nil by mouth from midnight tomorrow, in at 7am Thursday morning in preparation for egg collection by general anaesthetic later that morning - I'm first on the list. This is the main difference between being treated privately compared to the NHS. At my previous egg collection I was heavily sedated so have vague recollections of what went on and my Hubster was in the room with me. They 'woke me up' and two nurses then walked/carried me to a bed in the treatment waiting ward. I was then shuffled out the moment I was 'compus-mentus' and sent home; at The Lister I'm knocked out via general, I won't be aware of the 'bum torpedo' (this is a term I picked up from a fellow IVFer for the diclofenac suppository they give you rectally before surgery to relax your womb - it's not a pleasant experience I can tell you, I'll let your imaginations work out why), and my Hubster won't be in theatre with me. I'll have my own room and can leave when I am discharged which should be roughly four hours after I've been in theatre - so when I'm ready to go home, not when they need me to go home. There are other differences with this treatment cycle compared to my first fresh cycle: I have been monitored very closely, I've had a lot of blood taken to monitor my hormone levels - this didn't happen at the Kings ACU and I think if had been monitored as closely as I am now I wouldn't have gotten so poorly last time round.
We're provisionally booked in for embryo transfer this Sunday (6 April) but I'm pretty confident that we'll go to Tuesday (8 April) for a blastocyst transfer. We've paid for a more advanced version of ICSI called IMSI - this stands for intra cytoplasmic morphologically-selected sperm injection. The main difference is that the swimmers will be selected by an extremely strong microscope (x600 times stronger than the one used for standard ICSI) and then injected into my eggs, this should give us the best chance possible of making fabulous mini-mes - together with the endometrium scratch I had a couple of weeks ago should encourage implantation.
So for the interim I'm at home, relaxing trying to put all the nonsense of the past few weeks that could have very easily interfered with our treatment to the back of my mind. I'm focusing my energy on making protein rich, healthy eggs and trying not to focus on the negative - I am repelling stress as there's only one thing that we need to focus on. I have acupuncture at 4pm so I'm certain I will remain zen like in preparation for egg collection and for the transfer of our mini-me(s).
I'll be back in a few days with a round up with how egg collection went - exciting times!
Laters x
Showing posts with label HCG. Show all posts
Showing posts with label HCG. Show all posts
Tuesday, 1 April 2014
Friday, 1 February 2013
My own harvest festival
Egg collection and after affects round up
Egg collection was on Wednesday 30 January 2013, its now Friday 1 February and I'm spending another day in bed - oh what I'm going through to get a mini-me - but I'd do it all again - in a heartbeat.
So on EC day I was super calm, chilled and if anything not nervous but EXCITED - really excited. This was the day that the Hubster's DNA and my DNA were going to join to make mini-mes - what's not to be excited about?!
I got told off for admitting to taking a sip of water by the embryologist but we were still allowed to go ahead with the procedure. I won't lie to you - it hurt like a MoFo but I was out of it at the same time so I only remember snippets. The Hubster stayed with me throughout, I have vague recollections of him stroking my hair throughout the whole process. I had a heartbeat monitor and not at any point did it increase, it was a nice constant 70bpm, even when I was told to "take a deep breath in" and then I felt a hot, sharp stabbing pain around my womb / ovaries. The hypnotherapy CDs are obviously working - being relaxed and positive is the name of the game so if you are going through IVF yourself, please chill (and if all else fails, listen to The Orb's little fluffy clouds - works every time - you're allowed to take your iPod in with you if need be, if it helps - do it!!!) I know I bled as I felt them clean me up. I don't recall saying this but every time the embryologist said "deep breath in" I said "no pain, no gain." I winced but I wasn't a pansy and I breathed. This was after all one of the most exciting days of my life. What I'm really chuffed that I remembered was seeing MY EGGS on the big fat plasma screen - I am soooooo glad I was with it for that as it was 100% awesome - there were loads of them! Screw the pain - this is so worth it.
Anyhow, in recovery I zonked out and slept on and off for about an hour. I could hear a lady in the neighbouring cubicle crying her eyes out prior to her EC - if my head wasn't as woozy and my legs worked I would've gone in there, given her a big hug and would've tried to change her fear to excitement. I can't see how getting yourself in such a tizz is going to help matters? Anyhow - I hope the sedative helped her chill - it most certainly did me and I felt the after affects of it for the rest of the day.
The long and short of it is: I had far more than 26 follicles by the time the embryologist started having a rummage (my ovaries obviously went into overdrive last weekend), they got 18, yes 18 eggs (woo hoo) and Hubster's swimmers stood up to the test and did us proud. Another embryologist came to see us once I'd come round from the sedative in recovery and told us that at least 9 of my eggs would be fertilised via ICSI and 6 via conventional IVF. As per the most recent swimmer analysis, the Hubster's swimmers were on the cusp of ICSI/IVF so why not treat them like that and do a combo? Brilliant, the staff at King's really are amazing and I am in awe of them. How cool would it be to tell people that you're an embryologist? Far more exciting than saying you work in Marketing - I really wish science had been made a lot more appealing when I was at school as I now find it all fascinating. I'm going to make it my mission to get my mini-me(s) interested in science and with a bit of luck they'll go one to do something as amazing as this.
Anyhow, I digress, do you want to know what the different is between ICSI and IVF? ICSI stands for: Intra-cytoplasmic sperm injection. This involves injecting a single swimmer directly into the egg to fertilise it - so the swimmer is given a helping hand. Here's a picture to show you the science bit - seriously - these guys are amazing for being able to do this:
Conventional IVF stands for in-vitro fertilisation, this literally means fertilisation in a glass - here's another picture for the science bit:
I am very chuffed that we are having both, the staff at Kings are keen to keep the whole process of baby-making as natural as possible so we have been lucky enough to have the best of both worlds. This however is where my frank honesty of how many eggs and swimmers successfully fertilised ends; I want to keep this private and don't really want the amount of embryos we have currently dividing away out there on the internet (you can understand that hey?) What I can tell you is that we have mini-mes growing in a petri dish and the embryologist called saying "I have amazing news" and it was amazing - lockdown was worth it and I am so excited about everything (despite feeling like a big fat pile of steaming poo). We're booked in for embryo transfer (ET) at 10:30am tomorrow morning (Saturday 2 February 2013). This would be a three day transfer, I'm hoping our little mini-mes stay strong and keep dividing evenly so they can get to blastocyst stage and we can have a five day transfer.
Here's a bit more science: check the image below to see how embryos develop. If you look at the very first embryo picture that has just two small circles in it - these circles represent the DNA from the mother and the father - how cool is that?! I figure that our mini-mes are currently at the eight cell stage, awesome, awesome, awesome. With a bit of luck the progesterone pessaries I'm now on will help one of my mini-mes implant in my nice, think womb - a blastocyst implantation is the aim.
Since my EC I have been feeling rough. The bloating I had with the HCG trigger shot has increased, I look about six months pregnant. It seems I have mild OHSS, it's quite uncomfortable and painful, I've felt queasy and have had some terrible trapped wind! Kings are checking up on me daily, I have a jug I need to pee in and I need to drink at least two litres of water / juice / tea etc a day, and I need to monitor my pee output. If my output declines rapidly I need to get myself to Kings quick sharp, if I start to feel breathless I need to get to A&E. I feel like crap but I'm still über optimistic - it is what it is and it will go soon enough - its just one of those things. I had yesterday off sick and I'm off sick again today - I was supposed to work form home but sitting up at a laptop for long periods of time is very uncomfortable (this post has been written in segments). Kings are calling me daily and they are concerned and keeping a close eye on me but I figure it'll be gone soon enough and I'll have a mini-me inside me :)
So that's it from me today, despite feeling like poo this is quite possibly the most exciting time of my life.
Catch ya later :) x
Egg collection was on Wednesday 30 January 2013, its now Friday 1 February and I'm spending another day in bed - oh what I'm going through to get a mini-me - but I'd do it all again - in a heartbeat.
So on EC day I was super calm, chilled and if anything not nervous but EXCITED - really excited. This was the day that the Hubster's DNA and my DNA were going to join to make mini-mes - what's not to be excited about?!
I got told off for admitting to taking a sip of water by the embryologist but we were still allowed to go ahead with the procedure. I won't lie to you - it hurt like a MoFo but I was out of it at the same time so I only remember snippets. The Hubster stayed with me throughout, I have vague recollections of him stroking my hair throughout the whole process. I had a heartbeat monitor and not at any point did it increase, it was a nice constant 70bpm, even when I was told to "take a deep breath in" and then I felt a hot, sharp stabbing pain around my womb / ovaries. The hypnotherapy CDs are obviously working - being relaxed and positive is the name of the game so if you are going through IVF yourself, please chill (and if all else fails, listen to The Orb's little fluffy clouds - works every time - you're allowed to take your iPod in with you if need be, if it helps - do it!!!) I know I bled as I felt them clean me up. I don't recall saying this but every time the embryologist said "deep breath in" I said "no pain, no gain." I winced but I wasn't a pansy and I breathed. This was after all one of the most exciting days of my life. What I'm really chuffed that I remembered was seeing MY EGGS on the big fat plasma screen - I am soooooo glad I was with it for that as it was 100% awesome - there were loads of them! Screw the pain - this is so worth it.
Anyhow, in recovery I zonked out and slept on and off for about an hour. I could hear a lady in the neighbouring cubicle crying her eyes out prior to her EC - if my head wasn't as woozy and my legs worked I would've gone in there, given her a big hug and would've tried to change her fear to excitement. I can't see how getting yourself in such a tizz is going to help matters? Anyhow - I hope the sedative helped her chill - it most certainly did me and I felt the after affects of it for the rest of the day.
The long and short of it is: I had far more than 26 follicles by the time the embryologist started having a rummage (my ovaries obviously went into overdrive last weekend), they got 18, yes 18 eggs (woo hoo) and Hubster's swimmers stood up to the test and did us proud. Another embryologist came to see us once I'd come round from the sedative in recovery and told us that at least 9 of my eggs would be fertilised via ICSI and 6 via conventional IVF. As per the most recent swimmer analysis, the Hubster's swimmers were on the cusp of ICSI/IVF so why not treat them like that and do a combo? Brilliant, the staff at King's really are amazing and I am in awe of them. How cool would it be to tell people that you're an embryologist? Far more exciting than saying you work in Marketing - I really wish science had been made a lot more appealing when I was at school as I now find it all fascinating. I'm going to make it my mission to get my mini-me(s) interested in science and with a bit of luck they'll go one to do something as amazing as this.
Anyhow, I digress, do you want to know what the different is between ICSI and IVF? ICSI stands for: Intra-cytoplasmic sperm injection. This involves injecting a single swimmer directly into the egg to fertilise it - so the swimmer is given a helping hand. Here's a picture to show you the science bit - seriously - these guys are amazing for being able to do this:
Conventional IVF stands for in-vitro fertilisation, this literally means fertilisation in a glass - here's another picture for the science bit:
I am very chuffed that we are having both, the staff at Kings are keen to keep the whole process of baby-making as natural as possible so we have been lucky enough to have the best of both worlds. This however is where my frank honesty of how many eggs and swimmers successfully fertilised ends; I want to keep this private and don't really want the amount of embryos we have currently dividing away out there on the internet (you can understand that hey?) What I can tell you is that we have mini-mes growing in a petri dish and the embryologist called saying "I have amazing news" and it was amazing - lockdown was worth it and I am so excited about everything (despite feeling like a big fat pile of steaming poo). We're booked in for embryo transfer (ET) at 10:30am tomorrow morning (Saturday 2 February 2013). This would be a three day transfer, I'm hoping our little mini-mes stay strong and keep dividing evenly so they can get to blastocyst stage and we can have a five day transfer.
Here's a bit more science: check the image below to see how embryos develop. If you look at the very first embryo picture that has just two small circles in it - these circles represent the DNA from the mother and the father - how cool is that?! I figure that our mini-mes are currently at the eight cell stage, awesome, awesome, awesome. With a bit of luck the progesterone pessaries I'm now on will help one of my mini-mes implant in my nice, think womb - a blastocyst implantation is the aim.
Since my EC I have been feeling rough. The bloating I had with the HCG trigger shot has increased, I look about six months pregnant. It seems I have mild OHSS, it's quite uncomfortable and painful, I've felt queasy and have had some terrible trapped wind! Kings are checking up on me daily, I have a jug I need to pee in and I need to drink at least two litres of water / juice / tea etc a day, and I need to monitor my pee output. If my output declines rapidly I need to get myself to Kings quick sharp, if I start to feel breathless I need to get to A&E. I feel like crap but I'm still über optimistic - it is what it is and it will go soon enough - its just one of those things. I had yesterday off sick and I'm off sick again today - I was supposed to work form home but sitting up at a laptop for long periods of time is very uncomfortable (this post has been written in segments). Kings are calling me daily and they are concerned and keeping a close eye on me but I figure it'll be gone soon enough and I'll have a mini-me inside me :)
So that's it from me today, despite feeling like poo this is quite possibly the most exciting time of my life.
Catch ya later :) x
Tuesday, 29 January 2013
Ready or not...
In T minus 11 hours the Hubster and I will be at King's ACU; I'll be sedated, in theatre having my eggs harvested: OH MY GOD!!!
Breathe Johanna, breathe!
Normally I am getting my jabs ready around about now (started writing at 7:30pm in case you were wondering about the time lapse), but not tonight - I did the last one of those bad boys last night - happy days. The last buserelin, doo-lally jab was dispatched at 18:45, the one and only HCG trigger shot was done at 21:03 - exactly 36 hours before egg collection.
The last buserelin (doo-lally) jab
The one and only HCG trigger shot box that has been sitting in my fridge for just over three months
And the pre-loaded injection pen - natural at this jabbing malarkey now!
As promised the HCG trigger shot has "made me feel like crap." I woke up this morning looking like I was five months pregnant from all the bloating, my ovaries have been aching (particularly when I have to go for a pee), I've been feeling very nauseous - happy days. The bloating does have a bonus, I was offered a seat on the way to work twice this morning (and I took both of them; I'm near enough pregnant eh?!) Only time will tell of I get full-blown OHSS, fingers crossed I'm through with the side affects.
So tomorrow is D-day, we're up nice and early, I will have to get to grips with yet another glamourous side of IVF, the anal suppository that I have to insert an hour before I leave - oh yeeeaaaaah! This forms the first part of the analgesia so I'm sure I'll be grateful for it when it comes to egg collection. Of course tomorrow is the day that the Hubster "gets to do his bit." I know this whole process is mainly about me but obviously the Hubster plays an absolutely vital role and gosh - he's going to have to perform under pressure tomorrow morning - I do feel a teeny bit sorry for him but then all the staff at Kings have seen this thing a million times before. So whilst the Hubster is doing his bit I'll be getting into my gown and getting ready for the intravenous injection of pethidine (a strong painkiller), and midazolam (a sedative) to make the procedure more comfortable.
With a bit of luck these follicles will have some nice juicy, ripe eggs in them ready for harvesting, that the Hubster has some super swimmers, and there is some serious fertilisation going on.
So that's it from me today as I need to try and get an early night. I'll update either tomorrow or Friday with how many eggs were collected and whether we're having IVF or ICSI (and I'll explain what the difference is).
Seriously exciting (but oh so scary stuff). It's all been leading up to this day - let's hope it's all been worth it. IT'S GONNA HAPPEN!!!
Catch ya later :) x
btw: this tune has been in my head all day: DJ Hype, Ready or Not - can't imagine why?! If you're into your d'n'b then you'll like this - enjoy :)
Breathe Johanna, breathe!
Normally I am getting my jabs ready around about now (started writing at 7:30pm in case you were wondering about the time lapse), but not tonight - I did the last one of those bad boys last night - happy days. The last buserelin, doo-lally jab was dispatched at 18:45, the one and only HCG trigger shot was done at 21:03 - exactly 36 hours before egg collection.
The last buserelin (doo-lally) jab
The one and only HCG trigger shot box that has been sitting in my fridge for just over three months
And the pre-loaded injection pen - natural at this jabbing malarkey now!
As promised the HCG trigger shot has "made me feel like crap." I woke up this morning looking like I was five months pregnant from all the bloating, my ovaries have been aching (particularly when I have to go for a pee), I've been feeling very nauseous - happy days. The bloating does have a bonus, I was offered a seat on the way to work twice this morning (and I took both of them; I'm near enough pregnant eh?!) Only time will tell of I get full-blown OHSS, fingers crossed I'm through with the side affects.
So tomorrow is D-day, we're up nice and early, I will have to get to grips with yet another glamourous side of IVF, the anal suppository that I have to insert an hour before I leave - oh yeeeaaaaah! This forms the first part of the analgesia so I'm sure I'll be grateful for it when it comes to egg collection. Of course tomorrow is the day that the Hubster "gets to do his bit." I know this whole process is mainly about me but obviously the Hubster plays an absolutely vital role and gosh - he's going to have to perform under pressure tomorrow morning - I do feel a teeny bit sorry for him but then all the staff at Kings have seen this thing a million times before. So whilst the Hubster is doing his bit I'll be getting into my gown and getting ready for the intravenous injection of pethidine (a strong painkiller), and midazolam (a sedative) to make the procedure more comfortable.
With a bit of luck these follicles will have some nice juicy, ripe eggs in them ready for harvesting, that the Hubster has some super swimmers, and there is some serious fertilisation going on.
So that's it from me today as I need to try and get an early night. I'll update either tomorrow or Friday with how many eggs were collected and whether we're having IVF or ICSI (and I'll explain what the difference is).
Seriously exciting (but oh so scary stuff). It's all been leading up to this day - let's hope it's all been worth it. IT'S GONNA HAPPEN!!!
Catch ya later :) x
btw: this tune has been in my head all day: DJ Hype, Ready or Not - can't imagine why?! If you're into your d'n'b then you'll like this - enjoy :)
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