Egg collection and after affects round up
Egg collection was on Wednesday 30 January 2013, its now Friday 1 February and I'm spending another day in bed - oh what I'm going through to get a mini-me - but I'd do it all again - in a heartbeat.
So on EC day I was super calm, chilled and if anything not nervous but EXCITED - really excited. This was the day that the Hubster's DNA and my DNA were going to join to make mini-mes - what's not to be excited about?!
I got told off for admitting to taking a sip of water by the embryologist but we were still allowed to go ahead with the procedure. I won't lie to you - it hurt like a MoFo but I was out of it at the same time so I only remember snippets. The Hubster stayed with me throughout, I have vague recollections of him stroking my hair throughout the whole process. I had a heartbeat monitor and not at any point did it increase, it was a nice constant 70bpm, even when I was told to "take a deep breath in" and then I felt a hot, sharp stabbing pain around my womb / ovaries. The hypnotherapy CDs are obviously working - being relaxed and positive is the name of the game so if you are going through IVF yourself, please chill (and if all else fails, listen to The Orb's little fluffy clouds - works every time - you're allowed to take your iPod in with you if need be, if it helps - do it!!!) I know I bled as I felt them clean me up. I don't recall saying this but every time the embryologist said "deep breath in" I said "no pain, no gain." I winced but I wasn't a pansy and I breathed. This was after all one of the most exciting days of my life. What I'm really chuffed that I remembered was seeing MY EGGS on the big fat plasma screen - I am soooooo glad I was with it for that as it was 100% awesome - there were loads of them! Screw the pain - this is so worth it.
Anyhow, in recovery I zonked out and slept on and off for about an hour. I could hear a lady in the neighbouring cubicle crying her eyes out prior to her EC - if my head wasn't as woozy and my legs worked I would've gone in there, given her a big hug and would've tried to change her fear to excitement. I can't see how getting yourself in such a tizz is going to help matters? Anyhow - I hope the sedative helped her chill - it most certainly did me and I felt the after affects of it for the rest of the day.
The long and short of it is: I had far more than 26 follicles by the time the embryologist started having a rummage (my ovaries obviously went into overdrive last weekend), they got 18, yes 18 eggs (woo hoo) and Hubster's swimmers stood up to the test and did us proud. Another embryologist came to see us once I'd come round from the sedative in recovery and told us that at least 9 of my eggs would be fertilised via ICSI and 6 via conventional IVF. As per the most recent swimmer analysis, the Hubster's swimmers were on the cusp of ICSI/IVF so why not treat them like that and do a combo? Brilliant, the staff at King's really are amazing and I am in awe of them. How cool would it be to tell people that you're an embryologist? Far more exciting than saying you work in Marketing - I really wish science had been made a lot more appealing when I was at school as I now find it all fascinating. I'm going to make it my mission to get my mini-me(s) interested in science and with a bit of luck they'll go one to do something as amazing as this.
Anyhow, I digress, do you want to know what the different is between ICSI and IVF? ICSI stands for: Intra-cytoplasmic sperm injection. This involves injecting a single swimmer directly into the egg to fertilise it - so the swimmer is given a helping hand. Here's a picture to show you the science bit - seriously - these guys are amazing for being able to do this:
Conventional IVF stands for in-vitro fertilisation, this literally means fertilisation in a glass - here's another picture for the science bit:
I am very chuffed that we are having both, the staff at Kings are keen to keep the whole process of baby-making as natural as possible so we have been lucky enough to have the best of both worlds. This however is where my frank honesty of how many eggs and swimmers successfully fertilised ends; I want to keep this private and don't really want the amount of embryos we have currently dividing away out there on the internet (you can understand that hey?) What I can tell you is that we have mini-mes growing in a petri dish and the embryologist called saying "I have amazing news" and it was amazing - lockdown was worth it and I am so excited about everything (despite feeling like a big fat pile of steaming poo). We're booked in for embryo transfer (ET) at 10:30am tomorrow morning (Saturday 2 February 2013). This would be a three day transfer, I'm hoping our little mini-mes stay strong and keep dividing evenly so they can get to blastocyst stage and we can have a five day transfer.
Here's a bit more science: check the image below to see how embryos develop. If you look at the very first embryo picture that has just two small circles in it - these circles represent the DNA from the mother and the father - how cool is that?! I figure that our mini-mes are currently at the eight cell stage, awesome, awesome, awesome. With a bit of luck the progesterone pessaries I'm now on will help one of my mini-mes implant in my nice, think womb - a blastocyst implantation is the aim.
Since my EC I have been feeling rough. The bloating I had with the HCG trigger shot has increased, I look about six months pregnant. It seems I have mild OHSS, it's quite uncomfortable and painful, I've felt queasy and have had some terrible trapped wind! Kings are checking up on me daily, I have a jug I need to pee in and I need to drink at least two litres of water / juice / tea etc a day, and I need to monitor my pee output. If my output declines rapidly I need to get myself to Kings quick sharp, if I start to feel breathless I need to get to A&E. I feel like crap but I'm still über optimistic - it is what it is and it will go soon enough - its just one of those things. I had yesterday off sick and I'm off sick again today - I was supposed to work form home but sitting up at a laptop for long periods of time is very uncomfortable (this post has been written in segments). Kings are calling me daily and they are concerned and keeping a close eye on me but I figure it'll be gone soon enough and I'll have a mini-me inside me :)
So that's it from me today, despite feeling like poo this is quite possibly the most exciting time of my life.
Catch ya later :) x
Day 11 of stims
Yesterday was such a full-on, emotional day that I just didn't have the energy required to focus enough for a blog post, so here goes.
I was right - there has been a lot of activity going on downstairs as I have a whopping 26 follicles - whoop whoop whoop and my gosh - they're large! Not quite large enough for egg collection (EC) on Monday but it will be happening on Wednesday. However, this means that I am now at a high risk of developing OHSS - boo. After my scan (which was fascinating) I saw one of the nurses (Laura) and she ran through with me when I would be taking my last buserelin and Gonal F jabs and what the scenario would be for either a Monday or Wednesday EC (and gave me an anal suppository for EC day - gosh this IVF shizzle is sooooo sexy eh?!) I then had to see a doctor, who ran through with us what all the risks are with OHSS and what would I like to do with regards to my treatment:
a) Cancel my treatment - NO WAY JOSÉ!!!
b) Freeze my eggs and then carry on with treatment at a later date - NO WAY JOSÉ AGAIN! The treatment options on the NHS aren't as generous as they used to be and with only getting one fully-funded full cycle on the NHS we're not doing that!
c) Continue with treatment - YES WAY!!!
Doc mentioned how healthy I am, said my womb lining looks nice and thick, the reason for my enthusiastic response is due to being so healthy so this is good. Nice thick lining is the way forward if I want a successful implantation - this is what all the co-enzyme q10 is for - to help encourage a succesful implantation.
However, my pains are going to get worse, when I take my HCG trigger shot at 9pm on Monday evening I'm going to feel crap afterwards (OHSS thrives under HCG), after EC I will feel momentarily better but my follicles will fill back up with liquid and I will start feeling like crap again and after embryo transfer (ET) and presuming pregnancy occurs - oh yes - I will feel even more crap! What happens (as explained in my previous post), after the ovaries start going a bit crazy and keep on producing follicles that keep expanding - (this is the cause of the pain - 26 follicles all around 18m in diameter each - how the hell is all of that fitting in my womb? No wonder I've been feeling uncomfortable?!) The follicles are filling with liquid, this can seep out into the abdomen (hence looking out for water retention and bloating), but this can also show itself in fat ankles, a shortness of breath, dark coloured pee, resulting in nausea and vomiting and God forbid a blood clot. If I get a lot of water around my tummy, I'll have a drain fitted and as long as we are comfortable changing the drain I can have this at home, worst case scenario I'll have to go into hospital. I have been reassured that at Kings they have only had to cancel one IVF cycle as a result of OHSS, and that as this is always treated it's not fatal. What is reassuring to know is that OHSS doesn't impact on the likelihood of IVF resulting in a pregnancy (nor does it harm a pregnancy), and the staff at Kings are going to be keeping an eye on me and will be calling me daily after EC to check up on how I am feeling.
So yesterday, the Hubster and I were buzzing with nerves but mainly excitement - I can't quite believe that after trying for yonks, jumping through hoops with the NHS to get treatment, and then lockdown we are finally here. To think that this time next week there could be oodles of mini-me embryos all dividing on a petri dish waiting to be transferred into my womb (baby-house - this is what I hope it will be known as for the next nine months). SO EXCITING!!!
I have never, ever wanted something as bad as I want this - please, please, please let it work. If you are reading this please pray to whatever deity rocks your boat that this works. I am most certainly going to mass tomorrow - I/we have never, ever wanted anything as bad as we want this - I need to start showing my face at mass more often anyhow so there's no better time to start than now in my opinion. The nurse said I am a textbook case so far and given our positive, cheery outlook and healthy living there is no reason why we won't be pregnant this time next month. She also said that the Hubster's swimmers improvement is "commendable!" How awesome is that?! We were told at the beginning of treatment we have 40% chance of success (which is high going by IVF standards - I think this must've improved with all of our healthy living?)
So I've spoken to work about the posibility of developing OHSS, I don't think it went in really but if I feel in the slightest bit squiffy I shan't be going in to work - this is too important. I do feel at the moment like I'm about to come on - my lower abdomen is very firm to the touch and I have been getting pangs in my left side by my left ovary - this makes sense as there are 14 follicles on that side (and by the feel of it as I am on stims now for another two days I wouldn't be surprised if more follicles rock up), my boobs have gone from being deflated a couple of weeks ago to being back to their pre-menstrual self - larger and a bit tender - so yes - I feel like I feel when I am about to ovulate. With regards to the foo'ju - I told the nurses they need to tell ladies this shizzle! Needless to say they cracked up - not everyone gets it apparently but still - I can't see the harm in forewarning ladies that they may get it?!
So exciting days ahead, in the meantime I need to keep an eye on myself, make sure I'm drinking lots of water and I need to monitor the colour of my pee. I know one person who has had OHSS as a result of IVF and she had to go into hospital and I know from her account that is excruciatingly painful. She did get two beautiful baby girls from her IVF stint (first go) though - Molly and Josie - they are gorgeous so it's worth it. Kids hey - what - us ladies go through to get them? A friend of mine and his wife are also having IVF, at Kings and their EC is on Monday, another friend I know has had just her fourth ET, another friend of mine has had several IVF journeys and is now going down the surrogacy route, a parent from my Beaver Scout group went through IVF seven times to get her lovely boy Jonnie and someone at work is currently expecting (and she has the most gorgeous bump - she is positively glowing) - her pregnancy is a result of her first IVF attempt. My point is that IVF and infertility needn't be the taboo that it is, it's more common than we think. I am convinced we will get pregnant - my friends are all popping babies out left right and centre at the moment and I'm not going to lie and say I don't find it hard as I do find it hard - very hard but this gives me hope; hope that our journey is going to be a short(ish) one by IVF standards and I am going to join my bessie mates and have a mini-me of my own.
I'm actually off to meet one of my bessie mates for brunch this morning so I need to get a move on - it's just us two this morning, her wee man (affectionately referred to as "The Dude") is hanging out with Daddy this morning whilst us girls chew the fat. Tomorrow marks 17 years to the day when I first clapped eyes on the Hubster so I may see if I can find him a little pressie to say thank you for being amazing (that means I have spent 50% of my life with my wonderful Hubster - eeek! We REALLY deserve a break and to be able to have our own family - 17 years shouldn't be sniffed at). We don't normally do stuff like that - spend lots of money on presents on anniversaries - that is NOT the key to a long-relationship: love, trust, laughter and honesty are, not excessive gift giving (but that lecture is for another time). BUT my lovely Hubster deserves a little something, even if it is a silly a present - just to say thank you don't you think?
I must dash - catch ya later :) xxx
